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American Society of Microbiology ABMM Sample Questions:

1. A clinical microbiology laboratory encounters a Gram-negative bacillus isolated from a bloodstream infection. The isolate exhibits resistance to multiple antibiotics, including carbapenems. Further phenotypic testing reveals the production of a metallo-beta-lactamase (MBL). Which of the following antibiotic combinations might still retain activity against this isolate?

A) Piperacillin-tazobactam
B) Ceftazidime-avibactam
C) Aztreonam
D) Aztreonam-avibactam

2. A patient develops a severe, rapidly progressive pneumonia with hemoptysis. Gram stain of the sputum shows numerous small, pleomorphic Gram-negative coccobacilli. Growth on Bordet-Gengou agar is observed. The MOST likely causative agent is:

A) Bordetella pertussis
B) Legionella pneumophila
C) Moraxella catarrhalis
D) Haemophilus influenzae

3. A patient develops a localized skin infection after being bitten by a tick. The infection is characterized by a slowly expanding erythematous rash with central clearing (erythema migrans). The MOST likely causative agent is:

A) Ehrlichia chaffeensis
B) Anaplasma phagocytophilum
C) Rickettsia rickettsii
D) Borrelia burgdorferi

4. A previously healthy 28-year-old female develops a severe, watery diarrhea after attending a picnic where she consumed potato salad that had been left unrefrigerated for several hours. Stool culture reveals numerous Gram-positive bacilli. Further biochemical testing shows the organism is beta-hemolytic on blood agar and produces a heat-stable enterotoxin. The MOST likely causative agent is:

A) Vibrio cholerae
B) Staphylococcus aureus
C) Bacillus cereus
D) Clostridium difficile

5. A patient with a history of travel to a tropical region presents with cyclical fevers and chills.Peripheral blood smear reveals the presence of merozoites and schizonts within erythrocytes. The absence of crescent-shaped gametocytes makes Plasmodium falciparum less likely. The MOST probable species is:

A) Plasmodium malariae
B) Plasmodium knowlesi
C) Plasmodium vivax
D) Plasmodium ovale

Solutions: